5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-phenyl-, ethyl ester
Ethyl 2-hydroxy-4-phenylpyrimidine-5-carboxylate
CAS: 188781-06-8
Molecular Formula: C13H12N2O3
5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-phenyl-, ethyl ester - Names and Identifiers
5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-phenyl-, ethyl ester - Physico-chemical Properties
| Molecular Formula | C13H12N2O3 |
| Molar Mass | 244.25 |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Melting Point | >260 °C (decomp) |
| pKa | 7.42±0.10(Predicted) |
5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-phenyl-, ethyl ester - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29335990 |
5-Pyrimidinecarboxylic acid, 1,2-dihydro-2-oxo-4-phenyl-, ethyl ester - Introduction
Ethyl (ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate) is an organic compound with the formula C15H14N2O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Properties: Ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate is a white crystalline solid with a unique chemical structure. It is almost insoluble in water at room temperature, but can be dissolved in commonly used organic solvents, such as ethanol, acetone, dichloromethane, etc.
Purpose: Ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate is an important intermediate compound that can be used to synthesize compounds with pharmaceutical activity. It has potential application value in the field of medicine, and can be used to synthesize anti-tumor, anti-inflammatory and anti-gout drugs.
Preparation method: The synthesis method of ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylic acid ester is complicated and is usually obtained by multi-step reaction. A common synthetic method is the reaction of 2-amino -4-phenyl -5-carboxylic acid ester with acetic anhydride, followed by hydrolysis and esterification to obtain the target product.
Safety Information: Specific safety information and toxicity data regarding ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate are lacking. As an organic compound, it may be irritating and dangerous. Appropriate laboratory safety measures should be taken during use and handling, such as wearing protective gloves, goggles and protective clothing, and avoiding contact with skin and eyes. At the same time, it should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
Properties: Ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate is a white crystalline solid with a unique chemical structure. It is almost insoluble in water at room temperature, but can be dissolved in commonly used organic solvents, such as ethanol, acetone, dichloromethane, etc.
Purpose: Ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate is an important intermediate compound that can be used to synthesize compounds with pharmaceutical activity. It has potential application value in the field of medicine, and can be used to synthesize anti-tumor, anti-inflammatory and anti-gout drugs.
Preparation method: The synthesis method of ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylic acid ester is complicated and is usually obtained by multi-step reaction. A common synthetic method is the reaction of 2-amino -4-phenyl -5-carboxylic acid ester with acetic anhydride, followed by hydrolysis and esterification to obtain the target product.
Safety Information: Specific safety information and toxicity data regarding ethyl acetate 2-hydroxy-4-phenylpyrimidine-5-carboxylate are lacking. As an organic compound, it may be irritating and dangerous. Appropriate laboratory safety measures should be taken during use and handling, such as wearing protective gloves, goggles and protective clothing, and avoiding contact with skin and eyes. At the same time, it should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:11:58
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